Two cases of influenza A (H1N2) variant virus infection have been laboratory-confirmed in persons who had pig exposure at the California Mid-State Fair, which occurred in Paso Robles, CA during July 17–29. Influenza A (H1N2) was also detected in a pig at the fair. When the H1N2 influenza virus is transmitted from pigs to humans, the resulting infection is called H1N2 variant (H1N2v).